Post Tue Sep 27, 2022 1:08 am

Sr. Scientist - Flow Cytometry Specialist at Novartis

The department of Immuno-Oncology & Hematology (IOH) research at the Novartis Institutes for BioMedical Research (NIBR) focuses on mechanistic analysis of host immune responses, the tumor microenvironment, and ex vivo engineered HSC therapies for hematopoietic genetic disease. We employ multidisciplinary approaches spanning from discovery of novel therapeutic targets to development of innovative treatment strategies, and flow cytometry, which is critical to our work in deciphering the immuno-biology of cancer and improving therapeutic strategies.

We are seeking a talented and highly motivated Senior Scientist with extensive experience in operating, maintaining and trouble-shooting multiple different types of flow cytometers for our state-of-the-art flow cytometry facility. This role requires expertise in flow cytometry technology, experience helping scientists with data acquisition, analysis, management, the ability to provide classroom and hands-on training to users, as well as aptitude and interest to establish new flow technology and bring it in-house.

Your responsibilities include:
•Perform daily instrument QC, as well as weekly and monthly maintenance of all instruments.
•Train new users and assist users with experimental design, data acquisition and analysis and ad hoc trouble-shooting of issues on cell analyzers.
•Assist users sort cells on BDFACSArias. Train users to self-operate the Sony MA900 cell sorter.
•Communicate with manufacturer’s technical support and FSEs to arrange preventive maintenance and repair of instruments.
•Assist facility manager to develop and/or optimize and enforce facility user guidelines, develop and/or optimize user training SOPs, instruments operating SOPs, and QC SOPs. And perform data management according to Novartis guidelines.
•Purchase and inventory lab consumables.
•Participate in facility team effort including preparation of in-house sheath buffers.
•Give presentations as needed to educate users with new capabilities.

•Bachelor’s Degree in Biology, Chemistry or Physics with 3 to 5 years of experience in the flow cytometry field. Or a Master’s Degree with 1 plus years of experience in flow cytometry.
•Expertise with BD cell analyzers and cell sorters including FACSCanto, FACSFortessa and AriaFusion.
•Experience with single-cell sorting, cell proliferation and cell cycle analysis.
•Excellent communication skills and strong presentation skills. Must be a team player who enjoys collaborating with colleagues, demonstrates patience, a willingness to help others, and an ability to explain complex principles clearly and concisely to all experience levels.
•A scientifically motivated self-starter capable of independently conceiving, conducting, and critically analyzing research with minimal or no supervision, and can work in a fast-paced and team-oriented environment.

•Familiarity with other flow cytometry instrument platforms, including Agilent NovoCyte flow cytometer, Sony MA900 cell sorter, Cytek Aurora, and Standard Bio Tools CyTOF is a plus.
•Proficiency with FlowJo data analysis software. Familiarity with FCS Express and SpectroFlo is a plus.

Apply online at: ... q=352684BR