2025-Chan et al-Sci Transl Med

[mleipold]

"Prior vaccination prevents overactivation of innate immune responses during COVID-19 breakthrough infection"
Leslie Chan, Kassandra Pinedo, Mikayla A. Stabile, Rebecca E. Hamlin, Shaun M. Pienkos, Kalani Ratnasiri, Stanford COVID-19 Biobank, Samuel Yang Andra L. Blomkalns, Kari C. Nadeau, Bali Pulendran, Ruth O’Hara, Angela J. Rogers, Susan P. Holmes , and Catherine A. Blish
Sci Transl Med. 2025, 17, eadq1086
https://doi.org/10.1126/scitranslmed.adq1086

- "Mass cytometry FCS files with deidentified metadata supporting this publication are available at Flow Repository (http://flowrepository.org) under repository ID: FR-FCM-Z77Q."
- "Sorry, you do not have access to the specified experiment."

[mleipold]

FR-FCM-Z77Q now available

[MarieIannone]

This 2025 paper by Chan et al. (Science Translational Medicine) was nicely reviewed in a recent TWiV podcast (This Week in Virology, episode 1191) by Vincent Racaniello and Alan Dove. The review starts at about 12 minutes into the podcast and continues until about 50:00. They briefly mention mass cytometry at 18:50!

https://www.microbe.tv/twiv/twiv-1191/
https://www.youtube.com/watch?v=nS_rlsFP9-E

Marie Iannone