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Markers for Myeloid derived suppressor cells (MDSCs)

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komal2000

Participant

Posts: 11

Joined: Mon Aug 29, 2016 12:55 pm

Location: University of Helsinki, Finland

Post Fri Dec 20, 2019 7:41 am

Markers for Myeloid derived suppressor cells (MDSCs)

Dear Lovely CyTOF People,

Soon, I am planning to run CyTOF. One of the goal is to identify Myeloid derived suppressor cells (MDSCs) in multiple myeloma and I am not familiar with the MDSC markers. Can any of you suggest me good CyTOF antibodies (markers) to define MDSCs.
Your help will be appreciated.


Sincerely
Komal
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singh423

Participant

Posts: 4

Joined: Mon Feb 12, 2018 10:42 pm

Post Fri Dec 20, 2019 4:03 pm

Re: Markers for Myeloid derived suppressor cells (MDSCs)

Hi Komal
follow this article
https://www.nature.com/articles/s41467-019-11338-y
Precisely look for figure 4i and Supplementary figure 10a for gating strategy, These are markers best known to identify Human and Monkey MDSCs
if you have further questions let me know.
Thanks
Amar
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komal2000

Participant

Posts: 11

Joined: Mon Aug 29, 2016 12:55 pm

Location: University of Helsinki, Finland

Post Mon Dec 23, 2019 9:08 am

Re: Markers for Myeloid derived suppressor cells (MDSCs)

Thanks Amar and Tomer. Your papers helped a lot.


Sincerely
Komal

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