Fri Dec 10, 2021 7:09 pm by TomerWeizmann
Hi Mike,
1. According to FDM they were defective in manufacturing, resulting in microscopic cracks (from what we could see sometimes visible under the microscope), or a not good seal at the area where the inner capillary of the nebulizer is touching the outer part (on the back side). Thus, allowing gas to enter and produce bubbles, which are clearly visible with the naked eye.
2. From what we know, and confirmed by FDM, there are at least three different lengths of nebulizers tips, but these were tested and do not affect performance (personally I prefer the long ones).
3. Bottom line is to check your data vs time for a consistent flow, and look for bubbles (stop/go) in the exposed part of the nebulizer when running. If you observe fluctuations, and you rule out clogs, the above may be the cause.
4. FDM agreed to validate our nebulizers and capillaries prior to sending them to us – this is a satisfactory solution for us. I leave it to them to troubleshoot with Meinhard etc.
5. Yes. As you have recommended, we have also sonicated the grounding nut with the Citranox, MeOH, DIW solution – we still observed fluctuations. But it is a good SOP. Thanks.
Thank you for all the help!
Tomer