Post Thu Mar 01, 2018 11:09 am

Statistical Analysis of Perturbation Response (SARA)

Hi everyone,

Has anybody used SARA analysis to compare between two treatment types? (as performed in Levine JH; Cell; 2015; Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis).

It was originally developed for quantifying phospho-protein induction following stimulation but I was wanting to try and use it to quantify mRNA induction. Unfortunately I have limited experience with R.