Post Wed Sep 18, 2019 4:15 am

Postdoctoral fellow position at University of Colorado

Subject: Postdoctoral fellow position in the lab of Dr. Elena Hsieh in the department of Immunology and Microbiology
Scope of the project: We recently identified a human hypomorphic IL-2Rβ defect that results in disrupted cytokine signaling, leading to autoimmunity and viral susceptibility (Fernandez and Baxter et al., 2019). The goal of the project is to understand the molecular and cellular mechanisms that govern immune derangements stemming from a defective IL-2Rβ, which will provide critical insights to manipulate this pathway for effective immunotherapy.

The successful candidate will learn and implement mass cytometry, single-cell RNA seq, and multiplexed ion beam imaging (MIBI) analysis. We are seeking an independent and highly motivated candidate with a PhD in immunology or microbiology, with experience in tissue culture, mouse work (including mCMV infection models), and flow cytometry. Of particular interest would be those with additional experience in CyTOF and/or scRNAseq. The successful candidate will have an appointment in the department of Immunology and Microbiology.
More information about the Hsieh lab can be found at:
ucdenver.edu/academics/colleges/medicalschool/departments/ImmunologyMicrobiology/faculty/departmental/Pages/HSIEH.aspx

Environment:
University of Colorado Denver, Anschutz Medical Campus: The 227-acre Anschutz Medical Campus is a completely new education, research and patient care facility, and the largest academic health center between Chicago, Texas and the West Coast. The campus provides adjacencies of clinical, educational and research facilities all within walking distance of each other, building a new culture of collaboration among clinicians, investigators and educators that invigorates research. The University of Colorado Denver has a rich infrastructure for research. The campus has a Comprehensive Cancer Center (NCI CCSG), comprising 17 technology cores and 14 programs, including bioinformatics and biostatistics, mass cytometry, flow cytometry, gene expression analysis, proteomics, gene targeting, DNA sequencing and microarray, antibody production, electron and confocal microscopy, and multipliexed imaging platforms (Vectra, Polaris, MIBI).
The Department of Immunology and Microbiology: The merged Department of Immunology and Microbiology currently consists of 42 primary and 48 secondary faculty whose research interests range from lymphocyte development, activation and signaling, to repertoire development, including positive and negative selection, immunodeficiency and autoimmunity. Robust programs on the microbiology side of the enterprise focus on innate immunity, microbial pathogenesis and infectious disease.

Salary and start date: salary is based on NIH standards, which are based on years of experience. The benefits are defined as part of the job classification established by the University of Colorado. Start date: immediately.

Application and inquiries: for inquiries and to express interest in this position, please send a CV, a cover letter describing past research accomplishments and future research interests and goals, and contact information of three references to Dr. Elena Hsieh at elena.hsieh@cuanschutz.edu.