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Metal-Conjugated NeutrAvidin for MHC Multimer Assays

PostPosted: Sat Feb 27, 2016 6:27 pm
by Ofir
This Fluidigm poster showcases metal-tagged tetramer assays for detection of CMV-specific T cells in PBMCs.
https://www.mblintl.com/assets/AAI-Post ... -final.pdf

Re: Metal-Conjugated NeutrAvidin for MHC Multimer Assays

PostPosted: Mon Feb 29, 2016 4:09 pm
by mleipold
Hi Ofir,

Are there plans for Fluidigm to sell the "proprietary amine-reactive metal-chelating polymer" mentioned in this poster?

Aside from the issue that some antibodies are happier with amine-chemistry, there are a lot of other proteins/probes out there which don't have thiol/Cys (eg, some of the lectins I used back at UofT).


Mike