Post Tue Apr 04, 2023 6:48 pm

2021-Lee et al-Nat Commun

"Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma"
Alexander H Lee, Lu Sun, Aaron Y Mochizuki, Jeremy G Reynoso, Joey Orpilla, Frances Chow, Jenny C Kienzler, Richard G Everson, David A Nathanson, Steven J Bensinger, Linda M Liau, Timothy Cloughesy, Willy Hugo, Robert M Prins
Nat Commun. 2021, 12, 6938
https://doi.org/10.1038/s41467-021-26940-2

- "Data availability Single-cell RNA sequencing raw data files are available in the Gene Expression Omnibus under accession number GSE154795 and CyTOF raw data files are stored at the Flow Repository under the ID FR-FCM-Z4LX. These files supply the data for Figs. 1–6 and Supplementary figs. 1–7. The raw single-cell RNA sequencing was aligned to the Genome Reference Consortium Human Build 38 (GRCh38, GCA_000001405.15) prior to analysis. The remainder of data that support the findings of this study, including multiplex IHC images and data files and processed CyTOF fcs files ready for analysis, are available from the corresponding author upon reasonable request"