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2020-Liang et al-preprint

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mleipold

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Posts: 2156

Joined: Fri Nov 01, 2013 5:30 pm

Location: Stanford HIMC, CA, USA

Post Tue Jun 02, 2020 4:55 pm

2020-Liang et al-preprint

"Sensei: How many samples to tell evolution in single-cell studies?"
Shaoheng Liang, Jason Willis, Jinzhuang Dou, Vakul Mohanty, Yuefan Huang, Eduardo Vilar, Ken Chen
bioRxiv, posted June 01, 2020
https://doi.org/10.1101/2020.05.31.126565

- will update when/if this is peer-reviewed and published

- resuses dataset from 2017-Chew et al-Proc Natl Acad Sci USA ; not publicly available

- cell number estimation tool available: https://kchen-lab.github.io/sensei/table_beta.html
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mleipold

Guru

Posts: 2156

Joined: Fri Nov 01, 2013 5:30 pm

Location: Stanford HIMC, CA, USA

Post Tue Jun 02, 2020 5:11 pm

Re: 2020-Liang et al-preprint

It's a recurring question: how many cells do I need to collect in order to confidently say I can see a certain cell type.

The Liang paper discusses that. The paper also mentions this other tool: https://satijalab.org/howmanycells

- disclaimer: I don't have experience yet with either tool, so I can't remark one way or the other about how useful (or valid) they are.

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